Sodium-Potassium-Exchanging ATPase

An enzyme that catalyzes the active transport system of sodium and potassium ions across the cell wall. Sodium and potassium ions are closely coupled with membrane ATPase which undergoes phosphorylation and dephosphorylation, thereby providing energy for transport of these ions against concentration gradients.

Also Known As:

Sodium, Potassium ATPase; ATPase Sodium, Potassium; Pump, Potassium; Pump, Sodium-Potassium; Sodium Pump; Sodium-Potassium Pump; Adenosine Triphosphatase, Sodium, Potassium; Na(+) K(+)-Transporting ATPase; Sodium, Potassium Adenosine Triphosphatase; ATPase, Sodium-Potassium-Exchanging; Adenosinetriphosphatase Sodium, Potassium; Pump, Sodium; Sodium Potassium Exchanging ATPase; Sodium Potassium Pump; ATPase, Sodium, Potassium; Adenosinetriphosphatase, Sodium, Potassium; Na(+)-K(+)-Exchanging ATPase; Na(+)-K(+)-Transporting ATPase; Potassium Pump; Sodium, Potassium Adenosinetriphosphatase; ATP phosphohydrolase (Na(+)-K(+)-transporting)

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Acid Anhydride Hydrolases
      - Adenosine Triphosphatases: 8623
        P-type ATPases: 226
        Sodium-Potassium-Exchanging ATPase: 656
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Carrier Proteins: 12999
    - Membrane Transport Proteins: 589
      - P-type ATPases: 226
        Sodium-Potassium-Exchanging ATPase: 656
      - Ion Pumps: 61
        Antiporters: 369
        Sodium-Potassium-Exchanging ATPase: 656
        Cation Transport Proteins: 22
        Sodium-Potassium-Exchanging ATPase: 656
  - Membrane Proteins: 10078
    - Membrane Transport Proteins: 589
      - P-type ATPases: 226
        Sodium-Potassium-Exchanging ATPase: 656
      - Ion Pumps: 61
        Antiporters: 369
        Sodium-Potassium-Exchanging ATPase: 656
        Cation Transport Proteins: 22
        Sodium-Potassium-Exchanging ATPase: 656

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Disease

Drug/Important Bio-Agent (IBA)